Spanish
Panama.- The Ministry of Health (Minsa) of Panama reported this Saturday that it ordered the withdrawal of three toothpastes of the Colgate commercial brand due to the effects it causes, including oral injury, pain, burning, inflammation of the gums and swelling of the lips.
"The products that must be withdrawn from the market in Panama are: Colgate Clean Mint with sanitary registration 114356 from Brazil; Colgate Total Clean Mint Toothpaste with sanitary registration 206275 from Brazil, and Colgate Clean Mint Toothpaste with sanitary registration 206112 from Mexico," specified an official statement.
The measure is supported by Resolution 165 of July 25, 2025, which "suspends registrations and orders the withdrawal from the market of the product Colgate Total Clean Mint Toothpaste".
This decision is based on a warning from the Brazilian National Health Surveillance Agency (ANVISA) regarding "reports from users of the product Colgate Total Clean Mint Toothpaste of effects including oral injury, pain, burning, gum inflammation and lip swelling".
The Brazilian agency made a decision to "seize all batches of this dental product, which contains in its formulation the substance stannous fluoride, which is an oral care agent".
The Ministry of Health said that the company Colgate Palmolive (CA) Inc., and any other distributor of Colgate Total Clean Mint toothpaste have until August 24th to submit the report of all batches withdrawn from the market of the products indicated and notify the National Directorate of Pharmacy and Drugs.
The Ministry of Health had already warned, on June 13, of possible adverse effects of stannous fluoride in toothpastes, although it then said that no reports of negative reactions related to toothpastes containing that chemical component had been received.
Tin fluoride is used as an active ingredient, present in various brands of toothpaste and mouthwashes worldwide, whose functions are to prevent cavities, maintain the oral cavity in good condition, and prevent dental plaque.
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The United States Food and Drug Administration (FDA), in its 'Over-the-Counter Drug Monograph for Human Oral Hygiene' (OTC in English), notes that this ingredient can be used safely and effectively if used properly and by products that, in their labeling, comply with the requirements of the OTC monograph and the established standards, the Minsa pointed out last June.
